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Dpp-4 Inhibitors

Januvia 100mg

Composition:
SitaglIPtin Phosphate Tablets IP
Dosage:
100mg
Manufacturer Name:
Msd Pharmaceutical Pvt Ltd.
Category
Dpp-4 Inhibitors
Tab/Inj/Jelly:
Tab
Commonly Known As:
Diabetes Meds
QuantityStrengthNew CustomerOld CustomerFree ShippingAdd to Cart
PriceUnitePriceUnite
30 Pills100mg47.71.5942.931.43
60 Pills100mg71.41.1964.261.07
100 Pills100mg990.9989.10.89
200 Pills100mg1780.89160.20.80

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300 Pills100mg2370.79213.30.71

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500 Pills100mg3450.69310.50.62

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1000 Pills100mg5900.595310.53

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2000 Pills100mg9800.498820.44

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**Januvia** (sitagliptin) is an oral medication used to manage type 2 diabetes by regulating blood sugar levels. It belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the levels of incretin hormones. These hormones help stimulate the release of insulin and reduce the production of glucose by the liver, especially after meals. Januvia is typically prescribed alongside diet and exercise, and can be used alone or in combination with other diabetes medications. It is usually taken once daily, with or without food. Januvia is well-tolerated, with a lower risk of causing hypoglycemia compared to some other diabetes medications. Common side effects include upper respiratory infections, headaches, and potential gastrointestinal issues. Regular monitoring of blood glucose levels is recommended to ensure effective treatment.

  • Effective in Blood Sugar Control: Januvia helps to lower blood sugar levels, especially after meals, by increasing the levels of insulin produced by the pancreas and decreasing the amount of sugar produced by the liver.
  • Convenient Dosage: Typically taken once daily, making it easier for patients to adhere to their medication regimen.
  • Weight-Neutral: Unlike some other diabetes medications, Januvia is generally considered weight-neutral, meaning it does not typically cause weight gain or loss.
  • Low Risk of Hypoglycemia: Januvia is associated with a lower risk of causing low blood sugar (hypoglycemia) compared to other diabetes medications, particularly when not used in combination with other glucose-lowering drugs.

How Januvia Works:

Januvia works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This enzyme normally breaks down incretin hormones, which are involved in regulating glucose levels. By inhibiting DPP-4, Januvia increases the levels of incretin hormones, leading to increased insulin release after meals and decreased glucose production by the liver.

  • Standard Dosage: The typical dosage of Januvia is 100 mg once daily.
  • Adjustment for Kidney Function: The dose may be adjusted based on the patient’s kidney function. Lower doses may be recommended for patients with moderate or severe renal impairment.
  • Kidney Function: Regular monitoring of kidney function is recommended, especially in patients with pre-existing kidney issues.
  • Pancreatitis: There have been reports of acute pancreatitis in patients taking Januvia, so it should be used with caution in individuals with a history of pancreatitis.
  • Hypoglycemia Risk: While Januvia itself has a low risk of hypoglycemia, the risk increases when combined with other medications like insulin or sulfonylureas.
  • Common Side Effects: Nasopharyngitis (common cold), headache, and upper respiratory infection.
  • Serious Side Effects: Pancreatitis, severe joint pain, allergic reactions including anaphylaxis, angioedema, and Stevens-Johnson syndrome.
  • Pancreatitis: Discontinue use if pancreatitis is suspected.
  • Allergic Reactions: Discontinue immediately if severe allergic reactions occur.
  • Heart Failure: Some studies suggest a possible increased risk of heart failure, especially in patients with pre-existing heart conditions.

Frequently Asked Questions (FAQ):

  • Can Januvia be taken with other diabetes medications? Yes, Januvia can be combined with other diabetes medications, but it’s essential to monitor for hypoglycemia when taken with insulin or sulfonylureas.
  • What should I do if I miss a dose? If you miss a dose of Januvia, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not take two doses at the same time.
  • Can Januvia be taken on an empty stomach? Yes, Januvia can be taken with or without food.
  • Is Januvia safe during pregnancy? Januvia should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. It’s essential to consult a healthcare provider.
  • How should Januvia be stored? Store Januvia at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
  • Does Januvia cause weight gain? Januvia is generally considered weight-neutral, meaning it typically does not cause weight gain or loss.

Conclusion:

Januvia is a valuable medication for managing type 2 diabetes, particularly due to its convenience and low risk of hypoglycemia. However, like any medication, it requires careful monitoring and consideration of potential risks and side effects. Always consult a healthcare provider for personalized advice.

Customer Review

Customer Reviews

Average Rating: 4.5 / 5





David A Wilson ,NY, USA





Januvia is a medication commonly prescribed for managing type 2 diabetes. It works by regulating blood sugar levels and is generally well-tolerated with minimal side effects. However, some users have reported digestive issues, so it's important to consult a healthcare provider for personalized advice.