Baclofen 25 mg

Composition:

BACLOFEN

Dosage:

25 mg

Manufacturer Name:

JOHNLEE

Tab/Inj/Jelly:

Tab

Commonly Known As:

Quantity	Strength	New Customer		Old Customer		Free Shipping
		Price	Unite	Price	Unite
30 Pills	25 mg	47.7	1.59	42.93	1.43
60 Pills	25 mg	71.4	1.19	64.26	1.07
100 Pills	25 mg	99	0.99	89.1	0.89
200 Pills	25 mg	178	0.89	160.2	0.80	Free Shipping
300 Pills	25 mg	237	0.79	213.3	0.71	Free Shipping
500 Pills	25 mg	345	0.69	310.5	0.62	Free Shipping
1000 Pills	25 mg	590	0.59	531	0.53	Free Shipping
2000 Pills	25 mg	980	0.49	882	0.44	Free Shipping

Baclofen is a muscle relaxant and antispastic agent commonly prescribed to treat muscle spasms, pain, and stiffness, particularly in conditions like multiple sclerosis and spinal cord injuries. It works by inhibiting neurotransmitter activity in the brain and spinal cord, reducing the occurrence of muscle contractions. Baclofen is typically taken orally in tablet form, though it can also be administered via an intrathecal pump for more severe cases. Common side effects include drowsiness, dizziness, and weakness. Long-term use can lead to dependence, and sudden discontinuation may cause withdrawal symptoms. It should be used with caution in individuals with kidney problems or a history of seizures.

Advantages of Baclofen

Muscle Relaxant: Baclofen effectively reduces muscle spasticity, helping to improve mobility and function in individuals with certain neurological conditions.
Improves Quality of Life: By alleviating discomfort and stiffness, it can enhance overall quality of life and facilitate rehabilitation.
Reduced Pain: It may help decrease pain associated with muscle spasms.
Oral and Intrathecal Administration: Baclofen can be taken orally or delivered via an intrathecal pump for severe cases.

Mechanism of Action

Baclofen is a GABA_B receptor agonist. By activating these receptors, it inhibits the release of excitatory neurotransmitters, leading to decreased nerve signal transmission and resulting in muscle relaxation.

Starting Dose: Typically, the starting oral dose for adults is 5 mg three times daily, which can be gradually increased.
Maintenance Dose: The maximum recommended daily dose is usually around 80 mg, but it varies based on individual tolerance and response.
Intrathecal Baclofen: Dosing for intrathecal administration is determined based on individual needs, usually starting at a low dose and adjusted according to clinical response.

Medical History: Inform your healthcare provider about any history of seizures, kidney problems, or psychiatric disorders.
Withdrawal: Do not abruptly stop taking baclofen, as this can lead to withdrawal symptoms. Taper the dose gradually under medical supervision.
Pregnancy/Breastfeeding: Discuss potential risks with your doctor if pregnant or breastfeeding.

Common side effects may include:

Drowsiness
Dizziness
Weakness
Fatigue
Nausea

Less common but more serious side effects may include:

Difficulty breathing
Confusion or hallucinations
Allergic reactions (rash, itching, swelling)

CNS Effects: Baclofen can cause sedation; caution is advised when operating machinery or driving.
Alcohol Interaction: Avoid alcohol as it may enhance the sedative effects.
Kidney Function: Dose adjustments may be necessary in individuals with impaired kidney function.

Frequently Asked Questions (FAQs)

1. Can baclofen be used for conditions other than muscle spasticity?

Baclofen is sometimes used off-label for conditions like chronic pain, but consult your healthcare provider before using it for other purposes.

2. How long does it take for baclofen to work?

Some patients may notice improvement within a few days, but it can take several weeks to achieve full benefits.

3. What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it’s almost time for your next dose. Do not double up.

4. Can baclofen be taken with other medications?

Always inform your doctor about all medications you are taking to avoid potential interactions.

5. Is baclofen addictive?

Baclofen is not considered addictive in the traditional sense, but dependency can occur if used long-term. Always use it under medical supervision.

Conclusion

Baclofen is an effective treatment for muscle spasticity but requires careful dosing and monitoring due to potential side effects and interactions. Always consult with a healthcare professional for personalized advice and management.

Customer Review

Customer Reviews

Average Rating: 4.5 / 5

David A Wilson ,NY, USA

Baclofen is a muscle relaxant commonly used to treat muscle spasms and spasticity, particularly in conditions like multiple sclerosis. It works by acting on the central nervous system to reduce muscle tone, providing relief from painful muscle contractions. While generally effective, it can cause side effects such as drowsiness, dizziness, and fatigue, so dosage adjustments may be necessary for optimal results.

Muscle Relaxant